Our Research — Fossati Lab

Targeting carbonic anhydrases in Alzheimer’s Disease (AD) and Cerebral Amyloid Angiopathy (CAA), effects on neurovascular function, neuroinflammation, clearance, AD pathology We are studying the effects of carbonic anhydrase inhib

Maryam HA 1/25/22 Maryam HA 1/25/22

Targeting carbonic anhydrases in Alzheimer’s Disease (AD) and Cerebral Amyloid Angiopathy (CAA), effects on neurovascular function, neuroinflammation, clearance, AD pathology

Read More

Mitochondria, caspases and death receptors in Aβ- induced brain vascular degeneration Our studies identified for the first time the TRAIL Death Receptors DR4 and DR5 as specific targets for Aβ oligomers binding in cerebral microvascul

Maryam HA 1/25/22 Maryam HA 1/25/22

Mitochondria, caspases and death receptors in Aβ-induced brain vascular degeneration

Read More

Cerebrovascular dysfunction and cardiovascular (CV) risk factors in Alzheimer’s Disease (AD) and Cerebral Amyloid Angiopathy (CAA) Our studies focus on establishing the mechanisms responsible for vascular cell death and neurovascular d

Maryam HA 1/17/22 Maryam HA 1/17/22

Cerebrovascular dysfunction and cardiovascular risk factors in Alzheimer’s Disease (AD) and Cerebral Amyloid Angiopathy (CAA)

Read More

Study of biomarkers for the diagnosis/progression of Alzheimer’s disease (AD), traumatic brain injury (TBI), and post-traumatic stress disorder (PTSD) Our lab is also conducting multiple translational studies for biomarker discovery, f

Maryam HA 1/17/22 Maryam HA 1/17/22

Study of biomarkers for the diagnosis/progression of Alzheimer’s disease (AD), traumatic brain injury (TBI), and post-traumatic stress disorder (PTSD)

Read More